PATHOPHYSIOLOGY DISFUNCTION

 
 
 
 
PATHOPHYSIOLOGY: NEURONTOLOGICAL DYSFUNCTION: ARTICLE #3

The purpose of this paper is to present a critical analysis of the following article related to neurontological dysfunction:

Brown, K.W., Wardlaw, J.M., White, T. & Walker, N. (1996). Caudate nucleus area in drug-induced parkinsonism. Acta Psychiatrica Scandinavica, 94(5), 348-351.

The authors state that their examination of caudate nucleus involvement in drug-induced parkinsonism (DIP) was conducted because earlier studies (several are cited) indicated that this brain area may influence the development of the condition, and there had been no follow-up research of this possibility. The background information was adequate in that it allowed the reader to not only understand the purpose of the study but also to understand why the research was needed.

Subject selection procedures as well as all data collection methods were described in enough detail to repeat the study or extend it. Further, the equipment used to obtain the CT scans was described as were the sites of the brain scanned (e.g., "...scans were obtained through the temporal lobes in order to measure the width of the medial temporal cortex at 2.5-mm slice intervals and 2.4-mm thickness, angled at 15 degrees caudad to the orbital-meatal line.")

Parkinsonian symptoms were assessed using a standardized procedure. The procedure itself was only briefly described but two references were provided for the reader who needs more detai


     
 
 
 
    

 

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