Endometriosis
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B. Distribution of symptomatology. B. Pelvic and extrapelvic endometriosis. B. Caucasians, African-Americans, Japanese. C. Transplantation of endometrial cells. 1. Transplantation theory. 2. Risks for menstrual regurgitation. VI. Natural history of endometriosis. VIII. Laparoscopy, ultrasound, and lasers. A major clinical problem, endometriosis ranks as the second most common gynecological disorder requiring medical and surgical treatment. Despite its widespread occurrence though, the pathophysiology of this disease remains controversial. Many believe that it results from the extrauterine transplantation of endometrial cells. The subsequent proliferation of such cells is then thought to produce symptoms. Various different treatment options are currently available for endometriosis. These include both medical and surgical approaches--each of which may be enhanced by laparoscopic techniques.
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nese women is twice that of Caucasian women. Thus far, though, an obvious explanation for this apparent difference has yet to be formulated (8:1-14).
Despite endometriosis' high prevalence and long history of clinical interest, the etiology of the disorder continues to be a topic of debate. This probably results from the lack of hard scientific data on the disease's pathophysiology (8:1). Our understanding of such mechanisms derives mainly from clinical observation rather than experimentation. Consequently, many hypotheses have been proposed and many misconceptions exist.
One of these misconceptions, celomic metaplasia, was one of the first theories to become widely accepted. For the most part, it maintained that the "mesophilial cells which comprise the peritoneal membrane underwent metaplasia and assumed the anatomic appearance and biologic response of the underlying genital tract mesenchyme (8:1-14)." The concept, however, does lack a strong scientific base.
Yet another misconception, the embryonic cell rests hypothesis held that cell rests of Mullerian origin might be present near developing Mullerian ducts. It was believed that hormonal stimulation after puberty might consequently result in ectopic endometrium
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IV Conclusion, III IV, Liss Inc, Academic Publishers, Obstetrics Gynaecology, Pathophysiology Celomic, Society's AFS, Thomas Rock, Chadha Buttram, III Diagnosis, endometrial cells, buttram eds current, eds current concepts, current concepts endometriosis, rock eds, eds modern, approaches endometriosis, modern approaches, thomas rock, endometriosis boston, concepts endometriosis york, 1991 pp, publishers 1991, ma kluwer, endometriosis york ny,
Approximate Word count = 2201
Approximate Pages = 9 (250 words per page)
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