The Epigenetic Theory

Epigenetic inheritance allows environmentally induced phenotypes to be transmitted between generations (Pal and Miklos, 1999, 19-37). The divergence of isolated populations may be first triggered by the accumulation of inheritable phenotypic differences which are followed later by genetic changes which strengthen these changes. If a quantitative trait is far from the optimum, it is advantageous to induce inheritable phenotypic variation. As the genotype gets closer to the peak, it is more favorable to canalize the phenotypic expression of the character, and this process leads to genetic assimilation. The divergence of inheritable epigenetic marks acts to reduce or eliminate the genetic barrier between two adaptive peaks. An epigenetic inheritance sys

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derlies genotype-by-environment interactions. The environment of a parent can affect their descendants by inheritably altering spigenetic signals. Epigenetic inheritance is the transmission of information from a cell or a multicellular organisms to its offspring without the information being encoded in the nucleotide sequence of the genes (Epigenetic, 2004). Epigenetic inheritance can be seen in humans in fibroblasts, which divide and give rise to new fibroblasts even though their genome is identical to that of other cells in the multicellular organisms. Epigenetic transmission of traits from one generation to the next also occurs in some organisms. Epigenetic inheritance systems allows cells of different phenotypes but identical genotypes to transmit their phenotype to their offspring, even though the phenotype-inducing stimulus is not present. There are basically three types of epigenetic inheritance systems: in the steady-state system, some metabolic patterns are self-perpetuating, and a gene, after being turned on, may transcribe a product that maintains the activity of that gene (Epigenetic, 2004). Descendants of the cell in which the gene was turned on will inherit this activity, though the original stimulus is
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Pal Miklos, Kremil Laboratory, Toronto Canada, Darwinian Lamarckian, Theoretical Biology, , Medical Hypotheses, References Epigenetic, Obshch Biology, epigenetic inheritance, epigenetic theory, epigenetic signals, 2004 epigenetic, gorelick 2004, complex diseases, reproductive characters, epigenetic factors, petronis 2004, neo-lamarckian medicine, Zh Obshch, meiotically-inheritable epigenetic signals, environmentally-alterable meiotically-inheritable epigenetic, 16 october 2004, pal miklos 1999, retrieved 16 october,
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Approximate Pages = 5 (250 words per page)

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