Tubular Reabsorption & Tubular Secretion
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1. Active and Passive Tubular Reabsorption The kidney receives roughly 20 percent of the cardiac output, and 99 percent of this blood flow goes to the renal cortex and one percent to the renal medulla (Stewart, 1998). Each kidney contains roughly one million nephrons, the filtration units of the kidney responsible for reabsorption and secretion. The function of the renal tubules is to reabsorb roughly 99 percent of the glomerular filtrate, and the proximal tubule reabsorbs 60 percent of all the solutes in the glomerular filtrate, including 100 percent of the glucose and amino acids, 90 percent of the bicarbonate and 80 percent to 90 percent of the inorganic phosphate and water (Stewart, 1998). The reabsorption is either active or passive. Most of the solute reabsorption is active, that is, it requires energy, and consumes oxygen. Active transport requires carrier molecules, and so is limited to their availability (Applegate, 2000, 382). Negative ions often follow passively the active transport of positive ions to preserve electrical neutrality. When active reabsorption of the solute from the tubule occurs, there is osmotic activity within the tubule, causing water to be reabsorbed by passive osmosis (Stewart, 1998). Urine is concentrated in the Loop of Henle by water reabsorption. This occurs because of the high concentration of the solute in the interstitium in the renal medulla. The Loop of henle is a counter current multiplier, allowing the high concentrat
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Tubular Secretion, Loop Henle, Tubular Reabsorption, stewart 1998, tubular secretion, loop henle, Retrieved Dec, Company Stewart, References Applegate, water reabsorption, carbon dioxide, carbonic acid, applegate 2000, 90 percent, vasa recta, osmotic pressure, , limb loop henle, vessels directing blood, body tubular secretion, blood vessels directing, osmotic pressure blood,
Approximate Word count = 984
Approximate Pages = 4 (250 words per page)
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