A new method of preparing vaccines against fungi using recombinant DNA technology and live fungi has been developed (NIH, 2000). The vaccine was produced against Blastomyces dermatiditis, a fungus which can cause a sometimes fatal blastomycosis lung infection in humans. The fungus was rendered harmless by using recombinant DNA technology to remove the W1-1 gene from the fungus. This gene is thought to be responsible fo
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