ADULT PRIMARY CARE
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Systemic Lupus Erythematosus (SLE) is a multi-factorial, multi-systemic, autoimmune disease that tends to affect women (10:1) mostly in the 2nd and 3rd decades of life. The disease is more common in Blacks than in other races and symptomatic manifestations of the disease are brought about as a result of the deposition of antigen-antibody complexes in capillary networks and specific visceral organs (Tierney et al., 1998). The disease tends to produce a pattern of relapse and remission and though it is mostly associated with low mortality, it can in some cases be very aggressive resulting in a rapid deterioration of the patient, ending in death.The activation of B-cells both by genetically predetermined events and environmental triggers, which are currently unknown, leads to the loss of self recognition and is the main cause of morbidity in SLE. According to Kumar et al.(1997) The array of antibodies that are produced as a result of the overactive plasma cells tend to form complexes with corresponding antigens and directly lead to tissue damage by creating an exaggerated hypersensitive state. These antibodies tend to be destructive toward the skin, kidneys, serous membranes, joints and heart. Though SLE can be easily identified by the clinician when its presentation is classic, many patients tend to present in more subtle and puzzling ways. Systemic features of SLE can include fever, malaise, anorexia, and weight loss, but ar
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Some common words found in the essay are:
MANIFESTATIONS SLE, Procainamide Quinidine, Erythematosus SLE, Arthritis RA, SLE Pericarditis, Bulman Hunder, RA TREATMENT, According Kumar, SLE Alopecia, Lupus Erythematosus, lupus erythematosus, systemic lupus, systemic lupus erythematosus, joint pain, et al, disease tends, 2nd 3rd decades, tierney et, changes x-ray, main cause, organ damage, mcp joints, 1997 systemic lupus, tierney et al, et al 1998,
Approximate Word count = 1071
Approximate Pages = 4 (250 words per page)
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