tion of the same gene, leading to reduced, but not eliminated, HPRT activity. A partial deficiency may also result in nephrolithiasis, gouty arthritis, and some neurological manifestations.
HPRT is located on the x-chromosome and is a recessive trait, so only males are affected. Since male Lesch-Nyhan patients are not capable of fathering children, women can be carriers of the syndrom
Lesch-Nyhan Syndrome. (1969, December 31). In LotsofEssays.com. Retrieved 03:50, April 20, 2024, from https://www.lotsofessays.com/viewpaper/1698923.html