Also, the accumulation of another neurotransmitter, epinephrine, can produce dysphoria and agitation (2:299). Finally, cocaine suppresses activity in the brain centers responsible for fear and panic (2:300). This suppression, which may contribute to the feelings of euphoria, can seriously affect a person's judgement (2:300).
At doses large enough to result in intoxication, hallucinations, grandiosity, impulsiveness, and extreme psychomotor activation can occur (2:300). In fact, such adverse effects are observed in 80% of regular users (2:300).
Cocaine intoxication and addiction do have an extremely negati
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