Hepatocytes

In the normal adult liver, it has been estimated that there are about 250 billion hepatocytes (1:xxix). Indeed, the liver is the largest visceral organ in mammals; in man, its weight is approximately 1.5 kilograms (2:8).

The development of the liver parenchyma starts from entodermal cells which grow into the mesenchyma of the septum transversum (2:8). The organ and its hepatocytes generally perform two major actions. At one end of the spectrum, the liver serves an ingestive function; at the other end, its secretory functions are exerted.

Hepatocytes comprise 80% of the livers volume and 60% of its total cell number (2:10). In histological sections, the parenchymal cells appear irregularly polygonal and form a walllike structure (muralium) of anastomosing plates. These plates tend to be onecellthick structures, although twocellthick plates also occur. The plates are b

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Approximate Word count = 798
Approximate Pages = 3 (250 words per page)

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