ics unless under a doctor=s supervision.
Wellbutrin is used for the treatment of major depression characterized by a prominent and relatively persistent depressed or dysphoric mood which interferes with normal daily functioning almost every day for a period of at least two weeks duration. Symptoms requiring Wellbutrin should include at least four of the following: changes in appetite; changes in sleep patterns; psychomotor agitation or retardation; loss of interest in usual activities or loss of sexual drive; increased fatigue; slowed thinking or impaired concentration; increased feelings of guilt and unworthiness; and suicidal ideation or attempts.
The precise mode of action of Wellbutrin is unknown, but it does not inhibit monoamine oxidase. It is a weaker blocker of serotonin uptake and norepinephrine than tricyclic antidepressants, and inhibits the reuptake of dopamine to some extent.
After oral administration, peak plasma levels are usually reached in two hours, followed by a biphasic decline. The average half li
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