r of the organism is the aquatic environment, but this is not conclusive (Ryan & Ray, 2004; Todar, 2009).
V. cholerae causes cholera; it produces cholera toxin which causes the diarrhea. The passage of the V. cholera bacterium through the gastrointestinal tract where is colonizes is the major contributor to an increased pathogenicity. When V. cholera is studied in vetro, pathogenicity is not as severe without the gastrointestinal villi where V. cholerae attaches to and colonizes. When it does colonize, it produces mucinase, a protease and chitinase, an amylase. Chitinase allows the bacterium to enter copepods and mucinase helps it to enter the gastrointestinal tract of a human being (Faruque & Nair, 2008; Merrell, Butler, Qadri, Dolganov,
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