d CK-MB at 25 to 30% (NYT, 2010; Schlattner, Tokarska-Schlattner, & Wallimann, 2006).
The CPK test is used to diagnose heart attacks and evaluate the cause of chest pain (Health Guide, 1998). A CPK test is done to The CPK test can also be used to understand the amount of muscle damage. Early dermatomyositis and polymyositis can be detected with this test and the test can be used to show carriers of muscular dystrophy or differentiate between malignant hyperthermia and postoperative infection (Anderson, 2007; Barohn, 2007; Medline Plus, 2010). Normal levels of CK or CPK are 38 to 174 units/L for males and 96-140 units/L for females. Normal levels of creatine kinase isoenzymes are 5% MB or less and normal levels of creatine are .6 to 1.2 mg/dL (Blood Book, 2007).
There are multiple illnesses related with CPK levels. For example, abnormally high levels of CPK indicate the possibility of brain injury or stroke, heart muscle inflammation or heart attack, convulsions, delirium tremens, electric shock, lung tissue death, muscular dystrophies, and dermatomyositis or polymyositis. In addition, hyperthyroidism or hypothyroidism, rhabdomyolysis, and pericarditis after a heart attack may yield abnormal CPK levels (Anderson, 2007; Barohn, 2007; Medline Plus, 2010).
Creatine Phosphokinase (CPK) Levels and Disease
CPK serum levels are elevated in several disease states and elevated levels can indicate the possibility of these conditions (Science Today, 2007). CK levels accompanying chest pain and acute renal failure are not elevated. Normal values range from 60 to 400 U/L (one unit is enzyme activity or the amount needed to catalyze 1 umol of substrate per minute (Armstrong & Golan, 2008).
Ck levels in the skeletal muscle are 98% CK-MM and 2% CK-MB and CK levels in the cardiac muscle are 70-80% CK-MM and 20-30% CK-MB. CK-BB is found in the brain, prostate, gut, lung, and thyroid and plasma have...